Cleaning of Pharma Pack Blister Machine

In this post Standard Operating Procedure of Cleaning of Pharma Pack Blister Machine in Pharmaceuticals is describe.

Purpose: To lay down operating procedure for the cleaning of Pharma pack blister machine.

Scope:  This procedure is applicable for

Responsibility:  Production Chemist

To supervise the activity

Pre-operating Check: Check no material or residue should be there.

Frequency:  Complete wet cleaning different product each time after use or for the same product 

and dry cleaning at the end of the shift 

Equipment used:  Pharma pack blister machine

Wet cleaning procedure:

1.   Ensure that the Main Switch is OFF

2.   Remove Hopper, Bowl and dispensing Chute, Channel guide for PVC web and its assembly from the 

M/c. and also remove dust collector located under bowl assembly.

3.   Clean all these assemblies IPA and then with DM water. And ensure that no residue of product 

is there.

4.   Mop the M/c. and conveyor with dry and clean cloth. Also clean the place where the equipment 

is to be kept and it’s surrounding.

5.   Remove printings Stereos from the drum set of printing assembly and also removes ink from the 

ink box and clean it.

6.   Clean the Sealing Roller and counter Sealing Roller so that no residue of product lies on it.

7.   Return the remaining quantity of Printed Aluminum Foil, and PVC to store and record these 

details in BMR.

Dry cleaning procedure:

1.   At the end of shift clean Hopper, Bowl etc. with clean and dry cloth and surrounding area of 

Pharma pack blister machine.