Cleaning of Multi Mill

In this post Standard Operating Procedure of Cleaning of Multi Mill in Pharmaceuticals is describe.

Purpose:   To lay down operating procedure for the cleaning of Multi mill.

Scope:   This procedure is applicable to

Responsibility:   Production Chemist

                             To supervise the activity

Pre-operating Check: Check no material or residue of previous product is there.

Frequency:   At the completion of batch or at the end of shift.

Equipment used:  Multi mill (GMP models)

Procedure for product change over:

1 Ensure that the switch is off.

2  Cover the electrical parts with plastic bag.

3 Untie bolts of hopper and remove from the mill.

4  Dismantle screen-holding plate from the mill. Remove the SS Screen from screen holding plate.

5  Dismantle rotor and beaters assembly from multi mill. Disassemble beaters from rotor.

6  Clean rotor, beaters, hopper, SS Screen, Screen holding plate and body of mill first with water 

till residue of all material is removed. Then thoroughly wash with DM Water.

7  Mop the rotor, beaters, hopper, screen holding plate and body of mill with dry and clean cloth. 

Also mop the surrounding area of the mill.

8  Dry the s.s. Screen by applying compressed air.

9  Assemble the rotor and beaters. The scraper beaters have to be in lowest position. Mount the 

rotor and beaters assembly on drive shaft.

10 Ensure that the beaters should be fixed with their knife-edge in forward direction.

11. Mention the entire activities in Daily Log Sheet.

Procedure for same product or at the end of shift:

1.  Remove the powder materials from multi mill and s.s screen of multi mill Clean the surrounding 

area of multi mill.