Learn the complete SOP for Cleaning of Autodiluter used in quality control laboratories. Step-by-step instructions, responsibilities, best practices, and FAQs to ensure accurate dilution and compliance.
SOP for Cleaning of Autodiluter
Maintaining laboratory instruments in optimal condition is essential for ensuring accurate results and regulatory compliance. This SOP for Cleaning of Autodiluter provides a clear and structured procedure to clean the autodiluter used for sample dilution in the Quality Control (QC) department.
Proper cleaning not only extends the life of the instrument but also prevents cross-contamination, ensures precise dilution, and maintains data integrity.
1.0 Objective
The objective of this SOP for Cleaning of Autodiluter is to establish a standardized and systematic procedure for cleaning the autodiluter to ensure consistent performance, accuracy, and compliance with quality standards.
2.0 Scope
This SOP applies to the cleaning of the autodiluter installed in the Quality Control department. It must be followed by all authorized personnel responsible for operating and maintaining the instrument.
3.0 Responsibility
Clear role allocation ensures accountability and compliance.
3.1 Performing (Doing)
- Technical Assistant
- Executive
3.2 Checking (Reviewing)
- Executive
- Manager
4.0 Accountability
- Head of the Department
The Head of the Department is accountable for ensuring the implementation and adherence to this SOP for Cleaning of Autodiluter.
5.0 Procedure – Cleaning of Autodiluter
Follow the below steps carefully to ensure proper cleaning:
Step 1: Power Down the Instrument
- Switch OFF the autodiluter.
- Turn OFF the mains power supply to ensure safety before cleaning.
Step 2: Clean the External Surface
- Use a dry, clean cotton cloth to wipe the outer surface of the instrument.
- Ensure no moisture enters electrical components.
Step 3: Clean the Syringe
- Wash the syringe multiple times using distilled water or purified water.
- Ensure complete removal of residual samples or reagents.
Step 4: Flush the Syringe
- Flush the syringe 2–3 times at full volume using purified water.
- This step helps eliminate internal residue and prevents contamination in subsequent use.
Step 5: Drying
- Allow the syringe to dry completely before reinstallation or further use.
- Do not use compressed air unless validated by the department procedure.
6.0 Abbreviation
- SOP – Standard Operating Procedure
Why Is SOP for Cleaning of Autodiluter Important?
Implementing a well-defined SOP for Cleaning of Autodiluter ensures:
- Accurate and reproducible dilution results
- Prevention of cross-contamination
- Compliance with GMP and regulatory guidelines
- Extended equipment life
- Reduced maintenance costs
Regular and proper cleaning safeguards analytical accuracy and supports overall laboratory efficiency.
Frequently Asked Questions (FAQs)
1. Why is it necessary to follow an SOP for Cleaning of Autodiluter?
Following a standardized procedure ensures consistent cleaning, prevents contamination, maintains accuracy in dilution, and supports regulatory compliance in quality control laboratories.
2. How often should the autodiluter be cleaned?
The autodiluter should be cleaned after each use or as per laboratory protocol. Routine cleaning helps maintain performance and avoid sample carryover.
3. Can tap water be used for cleaning the syringe?
No, only distilled water or purified water should be used. Tap water may contain impurities that can affect instrument performance and analytical results.
4. Who is responsible for verifying the cleaning process?
The Executive or Manager is responsible for checking and verifying that the SOP for Cleaning of Autodiluter has been properly followed.
5. What happens if the syringe is not properly dried before use?
Residual moisture may dilute samples inaccurately or cause contamination, leading to unreliable test results.
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