To avoid the product contamination as per cGMP.

2.0  SCOPE

This procedure applies to all manufacturing equipment used in Manufacturing (Mixing Stirrers, Blenders, Mixers, Scoops, Buckets, and Spatulas etc.).


Ø  Production Supervisor
Ø  General Workers


Ø Wear protective garments, gloves & mask etc if required before cleaning operation.
Ø Clean the equipment from solid residue with water first with aid of brush.
Ø Clean next with ZIP detergent solution (20% solution) or any other suitable detergent & soak them if necessary in detergent solution for 10 minutes.
Ø Wash detergent off the equipment with hot water to remove all traces of detergent.
Ø Airs dry the equipment then rinse with germicidal Alcohol solution (IPA 70%)
Ø Dry in air & affix “Cleaned” Label before covering with plastic sheet or storage in the cabinet.


Machinery/Equipment Cleaning Log Book


Ø  Head of Operation
Ø  Q.A Manager
Ø  Production Manager
Ø  Q.C Manager
Ø  Production Pharmacist


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