Stockley’s Drug Interactions Pocket Companion 2015 

Stockley’s Drug Interactions is a reference work that provides concise, accurate, and clinically relevant information to healthcare professionals. Monographs are based on published sources including clinical studies, case reports, and systematic reviews, and are fully referenced. Stockley’s Drug Interactions Pocket Companion has summarised this comprehensive work to create a small and conveniently-sized quick-reference text.

Stockley’s Drug Interactions Pocket Companion 2015

Stockley’s Drug Interactions Pocket Companion provides the busy healthcare professional with quick and easy access to clinically relevant, evaluated and evidence-based information about drug interactions. As with the full reference work this publication attempts to answer the following questions:

. Are the drugs or substances in question known to interact or is the interaction only theoretical and speculative?

. If they do interact, how serious is it?

. Has it been described many times or only once

. Are all patients affected or only a few?

. Is it best to avoid some drug combinations altogether or can the interaction be accommodated in some way?

Stockley’s Drug Interactions Pocket Companion 2014 contains over 2200 interaction monographs pertaining to specific drugs or drug groups. Each monograph in Stockley’s Drug Interactions was assessed by practising clinical pharmacists for its suitability for inclusion in the Pocket Companion. Broadly speaking interactions involving anaesthesia, the specialist use of multiple antiretrovirals, the specialist use of multiple antineoplastics or intravenous antineoplastics, and non-interactions were omitted. However, exceptions were made, particularly where there has been controversy over whether or not a drug interacts.

Claire L. Preston studied pharmacy at the University of Nottingham, graduating in 1998. She completed her pre-registration year in Ashford, Kent before working as a community pharmacist for several years. She then became a medicines management pharmacist at a Primary Care Trust in Kent where she undertook her Clinical Diploma. Claire started at the Pharmaceutical Press in 2007 as a Staff Editor on the British National Formulary and later became an Assistant Editor. Claire has been the Lead Editor for Drug Interactions for the Pharmaceutical Press since March 2012.


Following the familiar format of the Stockley products, the information in this publication is organised into a brief summary of the evidence for the interaction and a description of how best to manage it. The information is based on the most recent quarterly update of Stockley’s Drug Interactions at the time of going to press. This data is fully referenced and available at These references have not been included in the Pocket Companion to keep size to a minimum. Anyone interested in seeing our sources can consult Medicines Complete, or the full reference work of Stockley’s Drug Interactions.


Stockley’s Drug Interactions Pocket Companion is structured alphabetically for ease of use, with International Nonproprietary Names (INNs) to identify drug names. Cross references to US Approved Names (USANs) are also included where drug names differ significantly. Consequently an interaction between aspirin and beta blockers will appear under A, and an interaction between beta blockers and digoxin will appear under B. We have only used drug groups where they are considered to be widely recognised, hence beta blockers is used, but alpha agonists is not. The drug groups we have used are as follows:

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