description
of methods usually employed to enhance the bio availability of a drug front its
formulation has been included at the end of chapter 12. In addition to covering
various aspects of design of dosage regimens and application of pharmacokinetic
principles in clinical situations, the text conta a final chapter on Controlled
Release Medication to familiarize the students with the principles _involved in
the · design of innovative formulations.
We
feel that a concept is more readily appreciated and understood when illustrated
by a simple figure or a table. In order to exemplify the text, illustrations
have been used liberally throughout the book. At the end of every chapter, a
set of questions including numerical have been provided. which are
strategically designed to complement the text of each chapter and test the
student's grasp of the text and their ability to analyze and solve problems. If
this book can help to provide the reader with a clear understanding of the
basic concepts of biopharmaceutics and pharmacokinetics, then we would consider
our object as fulfilled.
We
acknowledge the contribution of hundreds of scientists who are dedicated to
improvement of drug therapy. We are also indebted to the authors of the various
books and articles mentioned in bibliography which became a major source of
information for writing this text. Special thanks are due to Professor W. A.
Ritschel for his timely help and inspiration. We are also grateful to all those
who helped in different ways during the preparation of this book especially for
their support, encouragement and constructive criticism, particularly to our
students for their suggestions. Further, we are appreciative of the publishers
who graciously volunteered to make the publication of this book a reality.
Lastly,
the authors would very much appreciate receiving critical suggestions for
improvement and refinement of the text in future.
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