1.0 OBJECTIVE:
To
lay down the operating procedure of Potentiometer.
2.0 SCOPE:
This
shall be applicable to the Potentiometer of Quality Control Laboratory.
3.0 RESPONSIBILITY:
3.1
Technical
Assistant/ Helper.
3.2
Q.C Analyst.
4.0 ACCOUNTABILITY:
4.1
Manager-Quality
Control.
5.0 MATERIAL AND
EQUIPMENT:
5.1
Potentiometer.
5.2
Sample quantity as
specified in monograph.
5.3
Solvent as
specified in monograph.
6.0 PROCEDURE:
6.1
Check that the
power supply to the instrument is switched “OFF” before cleaning.
6.2
Clean the
instrument according to SOP.
6.3
Check that the
instrument is connected to the stabilized power supply.
6.4
Switch “ON” the
main power supply.
6.5
On desktop double
click on “tiamo1.2” icon. Screen show “tiamo1.2” it will initialize program and
devices.
6.6
Preparation
message appears. Press “OK” to all.
6.7
Four options will
appear on the left side screen show. Workplace, database, method,
configuration.
6.8
Click on workplace
option. Four windows are seen. Run, method, report, live display 1.
6.9
Click on
“Tools/manual control”. Select dosing device and go to preparation function.
Press start. The burette tip should point in a waste beaker. This step rinses
the burette and removes any possible air bubble.
6.10 Before
doing titration check electrode input, dosing device & stirrer to be used
in the method (selected for titration).
6.11 In
workplace on RUN window click on METHOD to select the appropriate method.
6.12 Weigh
the standard/ sample in a beaker and add the appropriate solvent, place it on
the magnetic stirrer to be used & put the magnetic paddle into it. Dip
appropriate electrode assembly along with dispensing tip in the beaker just
above the stirrer bar.
6.13 Enter
sample name, batch no. LNB Ref Analyst name & sample size (for assay also
enter the equivalent weight also).
6.14 Click
on START a window with sample detail will appear on the screen press OK.
6.15 Titration
proceeds. After the titration is over burette goes for filling and then report
appears in the report window.
6.16 As
the experiment is over, remove the beaker, wash the electrode properly.
6.17 Record
the observations in usage log book (Annexure-I).
6.18 Report print:
6.18.1 Click
on “Data base”.
6.18.2 Open
the appropriate data base.
6.18.3 Select
the report to be print.
6.18.4 Click
on “Tools” on menu.
6.18.5 Open
“Report template”.
6.18.6 For
report of “Blank” determination select titer template.
6.18.7 For
report of “Titer” determination select titer/ titer with statistics.
6.18.8 For
“Short report” of assay determination select template 1 & for “Detail
report” of assay determination select template 2.
6.18.9 After
selecting appropriate template click on “open”.
6.18.10Click
on “PDF” a PDF file will be created, save it or take print out.
6.19 Precautions:
6.19.1 Check
the levels of electrolytes in electrode regularly and replenish.
6.19.2 For
exchange unit containing NaOH apply grease to piston every week.
7.0 REVISION LOG:
Revision No.
|
Effective Date
|
Reason
|
00
|
|
New
SOP
|
8.0 REFERENCES:
8.1
Not Applicable.
9.0 ANNEXURES:
Annexure 1: Usage
log book of potentiometer.
Annexure:
1
Usage
log book of Potentiometer
Date
|
Product/ Material Name
|
Batch No./ Lot No.
|
Time
|
Analysis performed
|
Analyzed by
|
Checked by
|
Remarks
|
|
Started at
|
Completed at
|
|||||||
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
10.0
ABBREVIATIONS:
Abbreviation
|
Expanded Form
|
SOP
|
Standard operating
procedure
|
&
|
And
|
No.
|
Number
|
Ltd.
|
Limited
|
Q.C
|
Quality control
|
Q.A
|
Quality assurance
|
QCEO
|
Quality control
equipment operations
|
Ml
|
Milliliter
|
Mv
|
Millivolts
|
Hz
|
Hertz
|
v/s
|
Verses
|
No comments:
Post a Comment