Cresol red solution Reagent Preparation SOP


Title: Standard operating procedure of Cresol red solution preparation for laboratory use.

1.0  OBJECTIVE:
To lay down the procedure of Cresol red solution for Laboratory use.
2.0  SCOPE:
This shall be applicable to the Quality Control Laboratory.
3.0  RESPONSIBILITY:
3.1  Q.C Analyst.
4.0  ACCOUNTABILITY:
4.1  Manager-Quality Control.
4.2  Head of the Q.C Department.
5.0  MATERIAL AND EQUIPMENT:
5.1  Glassware (2 beakers, 1 pipette, 1 spatula, 1 glass rod).
5.2  Magnetic stirrer.
5.3  Analytical weighing balance.
5.4  0.1g of cresol red R.
5.5  2.65ml of 0.1M sodium hydroxide.
5.6  20.0ml of alcohol R.
5.7  Purified water (q.s.).
6.0  PROCEDURE:
6.1  Firstly weigh 0.1g of cresol red R by using analytical weighing balance operate according to SOP.
6.2  Prepare 0.1M sodium hydroxide in other beaker.
6.3  Take 100.0ml of beaker and add 2.65ml of 0.1M sodium hydroxide and 20.0ml of alcohol in it.
6.4  Add 0.1g of cresol red R in it.
6.5  Mix it by using magnetic stirrer.
6.6  And dilute it to 100.0ml with purified water R.
6.7  Again mix it thoroughly by using magnetic stirrer.
6.8  Ready for use.
7.0  REVISION LOG:
Revision No.
Effective Date
Reason
00

New SOP

8.0  REFERENCES:
8.1  The European Pharmacopoeia. Vol-1. Official Monograph /Reagents: 2015, pp.425-536.
9.0  ANNEXURES:
9.1  Not Applicable.



10.0    ABBREVIATIONS:
Abbreviation
Expanded Form
SOP
Standard operating procedure
&
And
No.
Number  
Ltd.
Limited
QCR
Quality control reagent
Q.C
Quality control
ml
Milliliter
Vol
Volume


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