Acemetacin International Brand (Medicinal Forms)


Acemetacin International Brand (Medicinal Forms)


INDICATIONS AND DOSE:

Pain and inflammation in rheumatic disease | Pain and
inflammation in other musculoskeletal disorders |
Postoperative analgesia
BY MOUTH
Adult: 120 mg daily in divided doses, then increased if
necessary to 180

CONTRA-INDICATIONS

Active gastro-intestinal bleeding . active gastro-intestinal ulceration . history of gastrointestinal bleeding related to previous NSAID therapy . history of gastro-intestinal perforation related to previous NSAID therapy . history of recurrent gastro-intestinal haemorrhage (two or more distinct episodes) . history of recurrent gastro-intestinal ulceration (two or more distinct episodes) . severe heart failure

CAUTIONS

Allergic disorders . cardiac impairment (NSAIDs may impair renal function) . cerebrovascular disease . coagulation defects . connective-tissue disorders . Crohn’s disease (may be exacerbated) . elderly (risk of serious side effects and fatalities) . epilepsy . heart failure . is chaemic heart disease . parkinsonism . peripheral arterial disease . psychiatric disturbances . risk factors for cardiovascular events . ulcerative colitis (may be exacerbated) . uncontrolled hypertension.

SIDE EFFECT

▶ Common or very common Anxiety . appetite decreased . central nervous system disorders . diarrhoea . dizziness . drowsiness . fatigue . gastrointestinal discomfort .
gastrointestinal disorders . haemorrhage . headache . hypersensitivity . malaise . nausea . skin reactions . vomiting
▶ Uncommon Alopecia . eye discolouration . hepatic disorders . oedema
▶ Rare or very rare Acute kidney injury (more common in patients with pre-existing renal impairment) . agranulocytosis . anaemia . angioedema . asthma . bone marrow disorders . coma . confusion . constipation . depression . enanthema . eyelid oedema . haemolytic anaemia . hallucination . hearing impairment . hyperglycaemia . hyperhidrosis . hyperkalaemia . hypersensitivity vasculitis . hypertension . inflammatory
bowel disease . irritability . kidney injury (more common in patients with pre-existing renal impairment) . leucopenia . loss of consciousness . memory loss . meningitis aseptic (patients with connective-tissue disorders such as systemic lupus erythematosus may be especially susceptible) . muscle weakness . nephritis tubulointerstitial . nephrotic syndrome . oral disorders . pancreatitis . photosensitivity reaction . psychiatric disorders . psychosis . renal papillary necrosis . respiratory disorders . seizure . severe cutaneous adverse reactions (SCARs) . shock . sleep disorders . tachycardia . taste altered . thrombocytopenia . tremor . urinary disorder .
urine abnormalities
▶ Frequency not known Circulatory collapse . dyspnoea . fertility decreased female . heart failure . increased risk of arterial thromboembolism . increased risk of infection .
increased risk of ischaemic stroke . increased risk of myocardial infarction . optic neuritis . paraesthesia . respiratory tract reaction
SIDE-EFFECTS, FURTHER INFORMATION
For information about cardiovascular and gastrointestinal side-effects, and a possible exacerbation of symptoms in asthma, see Nonsteroidal anti-inflammatory drugs p. 1094.

International Brands (Medicinal Forms)

Sr. #
Brand Name
Dosage Form
Pack Size
Price
Manufacturer
1.
No licensed medicines listed.


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