Aceclofenac
International Brand (Medicinal Forms)
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INDICATIONS
AND DOSE:
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Pain and
inflammation in rheumatoid arthritis,
osteoarthritis and
ankylosing spondylitis
▶ BY MOUTH
▶ Adult: 100 mg twice daily
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CONTRA-INDICATIONS
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Active gastro-intestinal bleeding
.active gastro-intestinal ulceration . cerebrovascular disease . history of
gastro-intestinal bleeding related to previous NSAID therapy . history of
gastro-intestinal perforation related to previous NSAID therapy . history of recurrent
gastro-intestinal haemorrhage (two or more distinct episodes) . history of
recurrent gastro-intestinal ulceration (two or more distinct episodes) .
ischaemic heart disease . mild heart failure . peripheral arterial disease .
severe heart failure
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CAUTIONS
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Allergic disorders . avoid in Acute
porphyrias p. 1025 . cardiac impairment (NSAIDs may impair renal function) .
coagulation defects . connective-tissue disorders . Crohn’s disease (may be
exacerbated) . elderly (risk of serious side-effects and fatalities) . history
of cardiac failure . hypertension . left ventricular dysfunction . oedema .
risk factors for cardiovascular events . ulcerative colitis (may be
exacerbated)
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SIDE
EFFECT
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▶ Common or very common Diarrhoea . dizziness . gastrointestinal
discomfort . nausea
▶ Uncommon Constipation . gastrointestinal disorders .
oraldisorders . skin reactions . vomiting
▶ Rare or very rare Anaemia . angioedema . bone marrow disorders . depression
. drowsiness . dyspnoea . fatigue . haemolytic anaemia . haemorrhage . headache
. heartfailure . hepatic disorders . hyperkalaemia . hypersensitivity .
hypertension . inflammatory bowel disease . leg cramps . nephrotic syndrome .
neutropenia . oedema . palpitations . pancreatitis . paraesthesia . renal failure
(more common in patients with pre-existing renal impairment) . respiratory
disorders . severe cutaneous adverse reactions (SCARs) . sleep disorders .
taste altered . thrombocytopenia . tinnitus . tremor . vasculitis . vasodilation
. vertigo . visual impairment . weight increased
▶ Frequency not known Acute coronary syndrome . agranulocytosis .
asthma . confusion . hallucination . increased risk of arterial thromboembolism
. increased risk of ischaemic stroke . malaise . meningitis aseptic (patients with
connective-tissue disorders such as systemic lupus erythematosus may be
especially susceptible) . nephritis tubulointerstitial . optic neuritis .
photosensitivity reaction . platelet aggregation inhibition . respiratory tract
reaction
SIDE-EFFECTS, FURTHER INFORMATION For information about
cardiovascular and gastrointestinal side-effects, and a possible exacerbation
of symptoms in asthma, see Nonsteroidal anti-inflammatory drugs p. 1094
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International
Brands (Medicinal Forms)
|
|
Sr. #
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Brand
Name
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Dosage
Form
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Pack
Size
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Price
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Manufacturer
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1.
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Preservex 100mg
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Aceclofenac 100 mg
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60 capsule
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£9.63
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Almirall Ltd
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Reference: